Cynthia Kenyon On The Biology of Aging

January 10, 2012

The following is an extract from an article, The Genetics of Ageing, which was written by Cynthia Kenyon and originally appeared in Nature in March 2010.
“For many years, molecular biologists interested in regulatory mechanisms did not study ageing, as the tissue decline associated with ageing suggested a passive, entropic process of deterioration that occurred in a haphazard [...]

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My Favorite Resveratrol, Promising Results for Mimetic

August 22, 2011

On the front page of the NY TIMES – August 19,2011 –Nicholas Wade reported on Dr. Rafael de Cabo’s newly published study on the positive effects of a resveratrol mimetic SRT-1720 on obese mice.  
To read the entire NY Times article by Nicholas Wade, click here.
I have followed this study, but I have also followed another one, [...]

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Robert Kane Pappas on “The Staying Young Radio Show”

August 6, 2011

On Sunday, July 31st, filmmaker Robert Kane Pappas was the featured
on The Staying Young Radio Show.
Robert was interviewed by Judy Gaman, along with Dr. Walter Gaman
and Dr. Mark Anderson on new breakthroughs in the science of aging.
The audio from the program The Science of Aging with Robert K. Pappas is attached here commercial-free [...]

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Notes on the 2011 Harvard / Paul F. Glenn Symposium on Aging

June 22, 2011

One content note in the program for the David Sinclair/Bruce Yanker hosted aging Symposium certainly catches your attention. It’s the blurb at the bottom of Dr. Jonathan L. Tilly’s page outlining his presentation.
“Rewinding the Female Biological Clock for Fertility Reasons: An End to Menopause as Well?”
To me, this exemplifies the stunning hints of the deep [...]

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TO AGE OR TO NOT TO AGE TO AIR ON LINKTV

June 14, 2011

TO AGE OR NOT TO AGE will air on LINKTV this month beginning on Monday, June 20th at 11 am Pacific Time/2 pm Eastern Time.  
The airdates are as follows:
Monday, June 20th, 11:00 am PT/2:00 pm ET
Wednesday, June 22nd, 11:00 pm PT/2:00 am ET
Saturday, June 25th, 2:00 am PT/5:00 am ET
Saturday, June 25th,  3:00 pm PT/6:00 pm ET
LINKTV can [...]

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The Journey of a New Drug

May 16, 2011

A video blog and brief comment by Robert Kane Pappas
 

The accompanying clip touches on the stages of a drug’s development. What struck me is that the journey from research lab to doctor’s office has so many intervening points.  Remember, that in our capitalistic system, a “discovery” will not come to market unless it can be [...]

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The Epigenetic Regulation of Telomeres

March 28, 2011

This blog entry focuses on a specific aspect of telomere biology, the epigenetic regulation of telomeres as mediated by TERRA, a recently-discovered RNA. Most popular discussions related to telomeres and telomerase are still based on simplistic earlier models of telomerase biology which do not take TERRA into account. So are the increasingly-popular commercial approaches to [...]

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Aging and Disease — a comment by Robert Kane Pappas

March 15, 2011

Last week, Vince Giuliano wrote a probing blog about aging and disease, which can be found on this site and on agingsciences.com.  I contributed a video clip. One of his underlying points is that a disease which is cured by stimulating one of these regulator genes — for instance SIRT1 or mTOR –- will likely [...]

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Aging and Diseases — Video Blog

March 12, 2011

Everyone knows that old age can lead to many diseases and problems.  And sooner or later one of those diseases or problems will kill everybody.    But, what exactly is the relationship of aging to diseases?  The question leads to surprisingly interesting answers.
First, please have a look at this video for opinions of some prominent scientists:

Here, [...]

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The Power Hour With Joyce Riley

March 9, 2011

This morning, Wednesday, March 9th, filmmaker Robert Kane Pappas was the featured guest of Joyce Riley on the Power Hour with Joyce Riley, a syndicated radio program available nationally and internationally.   Robert was joined by fellow collaborator, Vince Guiliano, for a lively two-hour discussion on longevity sciences and their implications. 
The audio from the program is attached here commercial-free [...]

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