Posts tagged as:

Dr. Leonard Guarente

Sinclair’s recent breakthrough on SIRT1

March 26, 2013

http://extremelongevity.net/2013/03/08/anti-aging-drug-breakthrough-acheived/

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The Aging Tree

March 2, 2012

By Robert Kane Pappas
“The Low Hanging Fruit” 
When discussing aging interventions – slowing down the aging process – note that there are causal relationships between aging, age related diseases, health span and lifespan. 
To make a further distinction, the pace of the application of various breakthroughs can be broken down into a second hierarchy: think of it [...]

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The Three Legged Chair

February 8, 2012

an essay by Robert Kane Pappas
The political flap over the prominent and well-funded breast cancer advocacy group -Susan G. Komen for the Cure – cutting off financing for screenings at Planned Parenthood – was spoken about largely on a political Left/Right basis.  
In her New York Times essay on February 7th, Susan Love, M.D. poses [...]

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Notes on the 2011 Harvard / Paul F. Glenn Symposium on Aging

June 22, 2011

One content note in the program for the David Sinclair/Bruce Yanker hosted aging Symposium certainly catches your attention. It’s the blurb at the bottom of Dr. Jonathan L. Tilly’s page outlining his presentation.
“Rewinding the Female Biological Clock for Fertility Reasons: An End to Menopause as Well?”
To me, this exemplifies the stunning hints of the deep [...]

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The Journey of a New Drug

May 16, 2011

A video blog and brief comment by Robert Kane Pappas
 

The accompanying clip touches on the stages of a drug’s development. What struck me is that the journey from research lab to doctor’s office has so many intervening points.  Remember, that in our capitalistic system, a “discovery” will not come to market unless it can be [...]

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Aging and Disease — a comment by Robert Kane Pappas

March 15, 2011

Last week, Vince Giuliano wrote a probing blog about aging and disease, which can be found on this site and on agingsciences.com.  I contributed a video clip. One of his underlying points is that a disease which is cured by stimulating one of these regulator genes — for instance SIRT1 or mTOR –- will likely [...]

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Aging and Diseases — Video Blog

March 12, 2011

Everyone knows that old age can lead to many diseases and problems.  And sooner or later one of those diseases or problems will kill everybody.    But, what exactly is the relationship of aging to diseases?  The question leads to surprisingly interesting answers.
First, please have a look at this video for opinions of some prominent scientists:

Here, [...]

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Age Reversal – Video Blog

February 28, 2011

Age reversal appears to be a subject for science fiction, like the alchemist’s vision of turning lead into gold.  Yet, it can be induced on the cellular level.  If fact, for certain of our cells absolute aging-avoidance or age-reversal is absolutely  necessary for the continuation of life.
 Please see this short video segment.

Is aging necessary for [...]

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Practical Steps to Reduce the Risk of Alzheimer’s Disease

November 5, 2010

In a previous post (click here), Robert Kane Pappas highlighted the promising research results relating to Alzheimer’s disease (AD) based on one study by a team led by Gizem Donmez in Dr. Lenny Guarente’s Lab at MIT and another involving rapamycin, an anti-rejection drug that targets the mTOR gene.  Translating promising results in the lab [...]

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Alzheimer’s Research — Connecting the Dots

September 9, 2010

RKP Comments on Recent Articles on Promising Research Results Relating to Alzheimer’s Disease
The first article is a press release from MIT on the research conducted by Dr. Guarente’s Lab.  Click here to read the article.  The second, an article posted on PLoS One, describes the effect of  rapamycin on AD progression.  Click here to read [...]

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